Dual anti-inflammatory drugs

Taking dual anti-inflammatory drugs is very unwise since new research proves it is a significant cause of poor general wellness.

Dual anti-inflammatory drugs are dangerous; period.

Abstracts from the rheumatic and arthritic journals always make interesting reading; what is medicine saying about itself? In the January, 2008 edition, researchers remark on the undesirability of using more than one drug to manage pain; these are the reasons why.

  • Inadequate prescription by doctors.
  • Lack of discussion concerning over the counter painkillers between patients and their doctors.
  • Too easy an access to OTC analgesics.

They state that it is well established that serious diseases of the bowels may be caused by taking more than one non steroidal anti inflammatory drug.  

Further they hypothesized that taking of more than one NSAID would affect not only the gastrointestinal tract but also be associated with a general poorer quality of life; this is what they wanted to research.[1]

Using dual anti-inflammatory drugs is plain dangerous.

There are better ways to tackle the early symptoms of arthritis.

So, it is well established that taking anti inflammatory drugs can cause serious diseases of the gut, but little was known concerning the use of more than one NSAID.

These medications are used to reduce inflammation and pain, especially for joint conditions. Arthritis of one form or another affects at least 30 percent of all adult Americans; worse, in the near future at least 20% are likely to experience significant disability and limitations in their daily style.

These inflammatory and degenerative arthridites are the chief cause of such disability.

Non steroidal anti inflammatory drugs are one of the most commonly prescribed medications worldwide. Among individuals with arthritis, almost 30 percent report daily use of over the counter NSAIDs. Given the availability of both sources, many patients may be taking more than one.

How many are they swallowing, you may be asking? This despite the fact that it is now well established that taking multiple anti-inflammatory drugs often leads to adverse events, including serious gastrointestinal bleeds.

The researchers used the following methods. Patients from a particular medical group who confirmed that they took more than one anti-inflammatory drug in a period of six months were interviewed.

The results of their research is as follows. They discovered that 26 percent of the anti-inflammatory population were taking more than one NSAID; both might be on prescription, or one or both over the counter. For example, swallowing both aspirin and ibuprofen was not uncommon.

More important, taking more than one anti inflammatory drug was definitely associated with a worse health related quality of life. One quarter of the participants were suffering from chronic lower back pain and a half had either rheumatoid or osteoarthritis. 

The net result of their research was that taking more than one anti inflammatory drug was an important independent predictor of poorer general health by a massive 351 percent.

Their conclusions were as follows.

Patients often self manage their pain in order to improve their life style by taking two or more anti inflammatory drugs. But, by attempting to gain only symptom relief for their conditions they were placing themselves at a greater risk of complications and a poorer quality of life.

Worse, health providers were seemingly unaware of the risks their patients were taking.

Finally, taking high doses of anti inflammatory drugs, and especially more than one, is a vital concern for both doctors and their patients' overall safety.

Here are a few comments from researcher Dr Dan Murphy.

Non steroidal anti inflammatory drugs are used widely and are readily available, both over the counter and by prescription. These medications are associated with many side effects, including some that are catastrophic; for example gastrointestinal bleeding, kidney and liver damage, strokes and myocardial infarction.

Maximum doses

The maximum dose is defined as that amount of the drug above which you will almost certainly suffer harm from toxicity. And in any case, there is no increased pain relief by exceeding the maximum dose, so it's just plain dumb.

Which toxic side effects are most likely?

  1. stomach ulcers,
  2. kidney and liver damage,
  3. a chemical imbalance in the blood,
  4. death. Remember a man called Michael Jackson?


The exception that proves the rule about dual antiinflammatory drugs is morphine. It may be taken in combination with other medications but consider the following.

  • The combination of opioids with acetaminophen or anti-inflammatories is relatively safe in the shorter term.
  • Acetaminophen is toxic to the liver and kidneys when taken in large amounts or for a long period.

Morphine also causes severe constipation, amongst its many nasty side effects. By sedating the nervous system to reduce pain morphine also drastically decreases the nervous input the muscles of the bowel.

The solution to that problem isn't yet more medications with even more side effects, but Nature's simplest remedies. Read about beetroot constipation and this quick constipation relief page and for more information about SOLUBLE fibre and its effect on the colon.

Arthritis in lower back

Arthritis in lower back can absolutely ruin your life... but, there's hope with Chiropractic! ARTHRTIS IN LOWER BACK ...


After seven years I have just returned to my native South Africa. Yesterday I had lunch with a dear friend and patient who has suffered for years with her neck and back. Well, I ate. Not able to find another chiropractor to her satisfaction, she started taking Ibuprofen on a regular basis... three days ago she developed a jet-black stool: digested blood from a gastic ulcer. She nearly died... today she goes for scopes... at all costs avoid dual anti-inflammatory drugs.

Useful links

  1. Association of health‐related quality of life with dual use of prescription and over‐the‐counter nonsteroidal antiinflammatory drugs

Dual anti-inflammatory drugs

Dual anti-inflammatory drugs use is highly dangerous for the bowel.

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Interesting challenges of the day

1. Mr S is a 76 year old man with neck pain of some 9 months duration. Luckily, most of the discomfort is upper cervical which is only rarely arthritic; his lower cervical spine is a degenerative mess that I have left alone. After seven treatments his pain and stiffness is 50 percent better, and he is happy in the circumstances. He can sleep through the night now and that makes a huge difference.

2. Mr P is 32 year old man with very severe lower back pain radiating to the big toe which is 30 percent numb. He had an episode three weeks ago, took anti-inflammatories and was soon better as is typical of the medial disc herniation. But before it healed, after a trivia it came roaring back, much worse. The characteristic crossed sign was evident; sitting in a chair, straightening the right leg provoked severe left back pain and tingling in the leg. He is doing well.

3. Severe lower back pain is scary; just ask Mrs P. Just watching her get out of the car I she was in trouble; she had a slipped disc at L4 making her lean towards the opposite side; luckily she had no pain in the leg. Despite family pressure that this was far too severe for a chiropractor, she persevered. Within five days she was standing upright, and after two weeks almost pain-free. 

Despite a hectic job, she wisely took my advice and stayed home for what I call exercising bed rest.

4. Mr S has had lower back, groin and back of thigh and calf pain for fourth months.

He has a pincer deformity in the hip causing the stabs in the groin, and a degenerative facet causing the sciatica. Both are responding well to chiropractic and he is well pleased; sixty-five percent better after three treatments.

5. Mr T is a wise man; he has taken a warning TIA seriously and has lost 15 pounds, and has at least as much again to lose. A change to a low starch diet and half hour daily stroll has made the difference; but the walking is making his foot and back miserable. The expensive orthotic is hopeless; luckily his hips and back are fine, but he needs a simple heel lift; he has a short leg.

6. I too have had serious lower back issues, luckily fixed by my own chiropractor; so I too have to do my exercises, take care when lifting supers full of honey, gardening and using the chainsaw. Regaining the function of your spine is just as important as the pain.

7. My own granddaughter, only 7 is hypermobile giving her pelvic, knee and ankle issues. X-rays show a mildly dysplastic hip. Years ago we would have called it growing pains. She too regularly needs chiropractic care and luckily responds well. Increased range of motion is more difficult than too stiff in my opinion. Our care is for kids too.

8. This 65-year old lady is a serious gardener; every day she is bending, lifting and digging for 2 to 3 hours a day. It regularly catches her in the sacroiliac joint, so she has a treatment once a month that sorts it out. She does her lower back exercises faithfully.

9. This 88-year old lady is an inspiration; every day she is busy in the community. With a nasty scoliosis she manages very well with a chiropractic adjustment every six weeks and exercises faithfully done. 

10. Mr X is a 71-year old retired man who wants to continue with maintenance care every six to eight weeks; he had suffered from two years of lower back pain when he first came a few months ago. He has no discomfort now after 8 chiropractic treatments, but is aware that danger lurks.

11. Mrs C has been having severe headaches, and taking a lot of analgesics. It is a non-complicated upper cervical facet syndrome, and she is doing well.

12. Mr D is a 38-year old year man with chronic shoulder pain after a rotator cuff tear playing cricket. It responded well to treatment, but he knows he must do his exercises every day; for two years he could not sleep on that shoulder.

13. Mr D, a 71-year old man, has a severe ache in the shoulder and midback since working above his head. Trapped nerve tests are negative but he has advanced degenerative joints of Luschka; after just two treatments he is 50 percent better. Can we reach 90?

And so the day goes; chiropractors should not be treating the elderly most medical sites state but that is so much bunkum.

Do you have a problem that is not getting better?

Are you looking for a different slant on your pain?

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Interesting questions from visitors

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You helped me quite some time back with a soothing and professional response which turned out to be exactly correct. I now consult a local chiropractor. You write a superb newsletter, too.

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