Food and inflammation

Green pea and hummus salad

Food and inflammation in the body are undeniably connected.

Research and medical opinion is stressing the importance of foods that decrease inflammation.

And, for that matter, those foods that increase inflammation.



What's more, are inflammed joints not connected to red and angry blood vessels?

Is the inflammation in the brain quite different to the angry muscles suffering from polymyalgia?

Is the inflammation of gout in the big toe really that different to the leaky gut that causes severe ulcerative colitis in the large intestine?

Or are these all a similar process that is simply affecting different organs, perhaps because of other factors. For example, inflammation in blood vessels is more affected apparently by smoking than in other organs.

In a landmark lecture a veteran heart surgeon of over 5,000 open-heart surgeries is now suggesting that the medical advice of changing from animal fat to polyunsaturated fats, and the use of statins, is the reason that the insides of blood vessels gets redder and more inflammed as the years go by, and cardiovascular disease continues to rise.

It's astonishing to hear a heart surgeon recommending that we return to moderate use of butter rather than us polyunsaturated margarines. Read more of his lecture at foods to reduce inflammation; eat the foods that your grandmother served, not what your mother buys and cooks, he says.

This is very complex biochemistry, but research is pointing to the ratio of omega-6 /omega-3 which should be kept as low as possible to reduce inflammation.

That means staying away from seed oils like those from corn and sunflower, with a possible exception of canola, because they are high in omega-6. Instead use butter in moderation, and olive oil.

And increasing your omega-3 fatty acids. That means fatty fish like salmon, freshly ground flaxseed and regularly eating walnuts. Use the search this site function for more about these foods to reduce inflammation.


That also means avoiding beef and pork advertised as corn fed; it may be more tender than pasture raised animals, but it will also cause more pain in the body.

Research shows interestingly that true free range eggs have three times the amount of omega-3; that gets the ratio moving in the right direction.

Dark green leafy vegetables are now widely recognised to be anti inflammatory in nature.


Food and inflammation

Food and inflammation looks to the phytochemicals in fruit and salads and an increase in our omega-3 fatty acids.


Two of the first we'll consider are lutein and zeaxanthin; they best known function is in the retina where they absorbe high energy photons of radiation entering the eye; a deficiency is the main cause of age onset macular degeneration and cataracts. But they are also strong anti inflammatory.

The best sources of these carotenoids are dark green leafy vegetables, and in particular kale; unrefined corn and citrus too. 

All berries are known to contain phytochemicals called anthocyanins that have been shown to block a cox enzyme that is at the forefront of inflammatory arthritis.

Heart surgeon Dr Dwight Lundell fingers two factors; first high omega-6 fats, as mentioned above, but also refined starches that produce a strong glycemic reaction in the body. That raises blood sugar and causes obesity. Research shows that fat cells in adipose tissue themselves secrete inflammatory chemicals.

Then there is the highly inflammatory breakdown product of certain proteins; it's known as homocystein; this is a quite normal process, but the body immediately inactivates it by a process known as methylation.

In order for methylation to occur successfuly certain vitamins and minerals are needed; in particular vitamins B6, B12, choline and betaine; without them a vital enzyme needed will be in short supply.

Once again it's dark green leafy vegetables like kale and beet tops, and eggs, particularly those that are produced by free range hens.


Gout

Gout is a painful form of inflammatory arthritis affecting most often the large toe due to a build up of uric acid crystals in the joint.

It's one of the many conditions that responds well to going on an anti inflammatory diet, and in my case is provoked by too much citric acid fruits; in particular orange juice.

Diabetes

LTB4 is a pro inflammatory substance found in the target tissues of insulin; adipose tissue for example. It's raised in diabetes.

You'll find that large people always hurt; there are many reasons but the main one is that the highly glycemic foods they enjoy provoke firstly a blood glucose surge, followed by an insulin rush as the body desperately tries to store the sugar in fat cells and the liver, and releasing LTB4.

The circulating LTB4 then activates other cells like those in muscles and joints, and the linings of blood vessels, for example, making them red and angry; pain.

Scientists have found that LTB4 is the pro inflammatory factor causing oedema and pain, and even worse making the tissues insulin resistant; it's the underlying cause of type 2 diabetes.

In short there's a strong connection between our food and inflammation.


Bagels

Deep fried bagels made from refined white flour cooked in hot oil, usually with a high omega-6 content, and then covered with a sweet topping is often typified as the highly inflammatory food.

First it raises the omega-6 to omega-3 ratio; that's inflammatory.

Secondly, refined flour has had the choline removed that is the precursor to an enzyme required to methylate homocysteine; more inflammation.

And thirdly, the sugary coating stimulates the release of pro inflammatory LTB4. The net result is a lot of pain.

According to Wikipedia, in 2012 the fresh bagel sales approached US$700 million in the United States.

Olive oil

Unrefined extra virgin olive oil contains a phytochemical called oleocanthal; food and inflammation are undeniably connected.

Oleocanthal is a natural anti inflammatory compound that inhibits the Cox enzymes that are released from angry, red joints and muscles; it is a Cox inhibitor but acts without the side effects of drugs such as Bextra, Vioxx and Celebrex.

Oleoanthal gives olive oil the burn in the back of the throat that is notably absent from refined olive oil.


Inflammation

There are two pathways leading to inflammation in the tissues after injury. Omega-6 PUFAs like arachidonic acid in the damaged cartilage, say, is acted on by

  1. Cox enzymes to form inflammatory prostaglandins which act both on local tissue and distant cells by acting as endocrine agents or hormones.
  2. FLAP enzymes to form pro inflammatory LTB4.

On the other hand, omega-3 PUFAs are affected differently with beneficial effects inhibiting inflammation and a host of other processes such as allergic reactions and atherosclerosis.

This is complex biochemistry; if you're interested read more about eicosanoids at Wikipedia.

Food and inflammation have a profound affect on these processes; firstly by the kinds of fatty acids being consumed and secondly by the presence of the many phytochemicals like oleocanthal that protect us from an overly robust inflammatory reaction to a small stimulus.

Researchers for example, have found that those regularly enjoying seven or eight coloured foods each day have a 35% lower all cause of death. They have diverse effects such as better eyesight, meaning less accidents, better blood pressure, less allergic reactions, fewer side effects from medication and less cancer. Foold and inflammation are inseparably linked.

Try and enjoy this eight colors eggs Florentine as often as you can for a breakfast treat.


This photo incidentally I took before the days of keeping our own hens; just compare these free range cage free eggs; they have triple the omega-3.


› Food and inflammation



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Interesting challenges of the day

1. Mr S is a 76 year old man with neck pain of some 9 months duration. Luckily, most of the discomfort is upper cervical which is only rarely arthritic; his lower cervical spine is a degenerative mess that I've left alone. After seven treatments his pain and stiffness is 50 percent better, and he's happy in the circumstances. He can sleep through the night now and that makes a huge difference.

2. Mr P is 32 year old man with very severe lower back pain radiating to the big toe which is 30 percent numb. He had an episode three weeks ago, took anti inflammatories and was soon better as is typical of the medial disc herniation. But before it healed, after a trivia it came roaring back, much worse. The characteristic crossed sign was evident; sitting in a chair, straightening the right leg provoked severe left back pain and tingling in the leg. He's doing well.

3. Severe lower back pain is scary; just ask Mrs P. Just watching her get out of the car I she was in trouble; she had a slipped disc at L4 making her lean towards the opposite side; luckily she had no pain in the leg. Despite family pressure that this was far too severe for a chiropractor, she persevered. Within five days she was standing upright, and after two weeks almost painfree. 

Despite a hectic job, she wisely took my advice and stayed home for what I call exercising bed rest.

4. Mr S has had lower back, groin and back of thigh and calf pain for fourth months.

He has a pincer deformity in the hip causing the stabs in the groin, and a degenerative facet causing the sciatica. Both are responding well to chiropractic and he's well pleased; sixty five percent better after three treatments.

5. Mr T is a wise man; he's taken a warning TIA seriously and has lost 15 pounds, and has at least as much again to lose. A change to a low starch diet and half hour daily walk has made the difference; but the walking is making his foot and back miserable. The expensive orthotic is hopeless; luckily his hips and back are fine, but he needs a simple heel lift.

6. I too have had serious lower back issues, luckily fixed by my own chiropractor; so I too have to do my exercises, take care when lifting supers full of honey, gardening and using the chainsaw. Regaining the function of your spine is just as important as the pain.

7. My own granddaughter, only 7 is hypermobile giving her pelvic, knee and ankle issues. Xrays show a mildly dysplastic hip. Years ago we would have called it growing pains. She too regularly needs chiropractic care and luckily responds well. Increased range of motion is more difficult than too stiff in my opinion. Our care is for kids too.

8. This 65 year old lady is a serious gardener; every day she is bending, lifting and digging for 2 to 3 hours a day. It regularly catches her in the sacroiliac joint, so she has a treatment once a month that sorts it out. She does her lower back exercises faithfully.

9. This 88 year old lady is an inspiration; every day she is busy in the community. With a nasty scoliosis she manages very well with a chiropractic adjustment every six weeks and exercises faithfully done.  

10. Mr X is a 71 year old retired man who wants to continue with maintenance care every six to eight weeks; he had suffered from two years of lower back pain when he first came a year ago. He has no discomfort now after 8 chiropractic treatments, but is aware that danger lurks.

11. Mrs C has been having severe headaches, and taking a lot of analgesics. It's a non complicated upper cervical facet syndrome, and she's doing well.

12. Mr D is a 38 old year man with chronic shoulder pain after a rotator cuff tear playing cricket. It responded well to treatment, but he knows he must do his exercises every day; for two years he couldn't sleep on that shoulder.

13. Mr D, a 71 year old man, has a severe ache in the shoulder and midback since working above his head. Trapped nerve tests are negative but he has advanced degenerative joints of Luschka; after just two treatments he is 50 percent better. Can we reach 90?

And so the day goes; chiropractors shouldn't be treating the elderly most medical sites state but that's so much bunkum.



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Interesting questions from visitors

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