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ALZHEIMERS and EXERCISE

Archives of Neurology. 2009;66(11):1339-1344.

(Keywords: ALZHEIMERS and EXERCISE, ANAESTHETIC ALZHEIMERS, chiropractic help, exercise and cholesterol, causes of osteoporosis)

ALZHEIMERS and EXERCISE brings convincing new evidence confirming what we already know: mental and physical exercise help prevent Alzheimers disease.

Background

Loss of muscle strength is common and is associated with various adverse health outcomes in old age, but few studies have examined the association of muscle strength with the risk of Alzheimer disease (AD) or mild cognitive impairment (MCI).

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Objective

To test the hypothesis that muscle strength is associated with incident Alzheimers Disease and Mild Cognitive Impairment.

Participants

More than 900 community-based older persons, without dementia at the start of the research, had the strength of nine muscle groups measured.

Results

Over the next four years, 138 /900 persons developed Alzheimers. What was interesting was those who increased their muscle strength (with exercise) had a 43% decreased risk of developing Alzheimers.

"Increased muscle strength was associated with a decreased risk of Mild Cognitive Impairment, the precursor to Alzheimer's Disease."

Conclusion @ ALZHEIMERS and EXERCISE

These findings suggest a link between muscle strength (exercise), Alzheimer's disease, and cognitive decline in older persons.

The moral of the story

If you want to save your brain from decline, granny's too, get the bikes and your hiking boots out. Or suffer. Not only mental decline, but think too about the causes of osteoporosis, arthritis and the relationship between a heap of other exercise and cholesterol related diseases.

From Alzheimers-and-Exercise to Causes of Osteoporosis ...

CHOLESTEROL AND ALZHEIMERS

There is a proven link between raised cholesterol and Alzheimers, just as there is with ALZHEIMERS and EXERCISE. The EGGPLANT, or AUBERGINE as it is known in Europe has been proved to lower cholesterol, hence our Eggplant recipes page. Of course by applying exercise and cholesterol you are indirectly helping your brain too! Nice to do anyway, good for your back, good for your heart, good!

EGGPLANT RECIPES ...

ALZHEIMERS AND DIET

In a landmark study, reported in Neurology 2007;69, researchers followed 8000 nondemented 65-year olds for the next four years. Their conclusions are sobering:

"Results:

Daily consumption of fruits and vegetables was associated with a decreased risk of dementia.

Weekly consumption of fish was associated with a reduced risk of Alzheimers Disease and all causes of dementia but only among ApoE 4 noncarriers.

Regular use of omega-3 rich oils was associated with a decreased risk (of borderline significance) for dementia.

Regular consumption of omega-6 rich oils (without a compensatory increase in omega-3 rich oils or fish) was associated with an increased risk of dementia among ApoE 4 noncarriers.

In short:

If you are a carrier, fish and omega-3 fish oil might not help.

If you are a non-carrier, omega-3 rich fish certainly helps prevents Alzheimers.

Even in non-carriers, too much omega-6 (seed oil) puts you at higher risk of Alzheimers, unless you also take omega-3.

Use less seed oils, rather use olive oil, since you almost certainly don't know whether you are a carrier or not, eat more fatty fish anyway and (controversial, my thoughts) use butter and olive oil rather than seed oils for cooking (if your cholesterol levels are okay).

GENETICS: apolipoprotein E (APOE) 4 carriers

In research reported in Archives of Neurology Vol 64, Sept 2007, that memory decline is certainly in part genetic. Researchers followed three groups of people aged 50-69:

Carriers of the APOE 4 gene on two genes (homozygous)

Carriers of the APOE 4 gene on only one gene (heterozygous)

Non-carriers of the APOE 4 gene.

RESULTS

Of 214 participants, 48 showed no decline in memory, 126 showed decline in one test (mild memory loss), 40 showed decline in two tests (more severe loss).

40% of those carrying APOE 4 on two genes (homozygous) showed significant cognitive decline compared to only 8% of the second two groups.

Thought

We can't change our genetics. If you are a carrier of APOE 4 on both genes you are at risk, BUT 60% of this group did NOT show significant decline.
How can we make sure we are in the 60% group, and not the 40% group who showed severe mental decline? It is NOT set in concrete whether we will get Alzheimers or not. Our behaviour has a vital role to play.
In another study (Archives of Neurology, vol 67, Jan 2010) researchers found that the APOE gene affects blood flow (reduces it) to the brain, preceding the onset of dementia.
In short, couch potatoes who are carrying APOE 4 on both genes are highly likely to end up in the 40% group. Those who exercise vigorously are far less likely to have loss of cerebral blood flow, and the consequent memory decline.
Furthermore, couch potatoes who are NOT carriers can also end up with Alzheimers, due to decreased blood flow to the cerebrum, but the chances are much lower.

MEMORY AND SLEEP

Whilst your body may be a rest at night, your mind is a hive of activity, storing and saving the relevant information of the day in its data bank. But... those who sleep poorly have difficulty storing this information in the normal way. The result is short term memory loss and ultimately Alzheimers.

Good, deep, relaxing sleep if vital for each and every one of us. Those who sleep 6 or less hours a night will have short term memory loss.

ANAESTHETIC ALZHEIMERS

Tragically, during surgery a sudden drop in blood pressure may leave the brain gasping for oxygen... ANAESTHETIC ALZHEIMERS

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USEFUL LINKS @ ALZHEIMERS and EXERCISE

Arthritis ...

Exercise and Cholesterol

Mainly, we think of cutting out of animal fats as a way of reducing blood cholesterol. Whilst that is, in part, true, including certain foods (like fatty fish and oats) also will reduce cholesterol. There is also a very strong relationship between Exercise and Cholesterol ....

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ALZHEIMERS AND EXERCISE

Did you find this page useful? Perhaps forward Alzheimers and Exercise to a mentally healthy friend. Prevention is the recourse.

This site is not intended to diagnose, treat, cure, or manage any illness. Please consult your chiropractor.

The information is to the best of my ability at the time of writing accurate and correct. Queries, comments and corrections are very welcome.

SBI!